The birth weight of nude mice is about 1-2g; the weight of male mice at weaning is about 7-9g, and the weight of female mice is lighter, about 6-8g; the average daily feed consumption is 5g/100g body weight, and the average daily drinking water The consumption is about 6-7ml/100g body weight. The breeding cycle is from May to June. Nude mice have poor growth and development, low resistance, low fecundity, and poor motherhood. In order to improve the reproduction rate and survival rate, the breeding method of mating homozygous male mice with heterozygous female mice is generally used to obtain 1/2 homozygous offspring.
Nude mice are widely used in immunobiology, immunopathology, transplantation immunity, tumor immunity, viral and bacterial immunology experiments, leprosy, and thymus function research and parasitic infection, it can be used to establish human cancer xenograft tumor models and conduct research on chemotherapy with anti-tumor drugs.
